I assume you are asking this for security reasons.
Hey @girish. Thanks for your reply. Actually it depends!
For MySQL: It's a matter of running not into backup import/export stuff or facing data losses because of some DBMS bug. So there I just prefer to having a up2date DBMS because in the past I faced one or two major issues with productive software where patching the systems could have prevented it.
For apache2: Yes, I think no application really relies on the version nor it's super likely to hit a bug in it. Of course I faced apache2/nginx module bugs in the past but that's quite rare. Nevertheless it would help to have an up2date version at that point as well to prevent cases like that and sometimes security issues are fixed there as well.
For PHP: Indeed this is the most relevant part for your deployed websites. In the past I just had to care about major PHP releases; minor versions never broke anything for me and had never been a requirement for any software I saw. Of course, security matters here as well.
Thanks for clarifying which software of LAMP is managed by the platform/OS and which is managed by Cloudron itself. That gave a better insight for me.